NF-κB inhibitors, unique γ-pyranol-γ-lactams with sulfide and sulfoxide moieties from Hawaiian plant Lycopodiella cernua derived fungus Paraphaeosphaeria neglecta FT462

LC-UV/MS-based metabolomic analysis of the Hawaiian endophytic fungus Paraphaeosphaeria neglecta FT462 led to the identification of four unique mercaptolactated γ-pyranol–γ-lactams, paraphaeosphaerides E–H (1–4) together with one γ-lactone (5) and the methyl ester of compound 2 (11). The structures...

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Detalles Bibliográficos
Autores principales: Li, Chun-Shun, Sarotti, Ariel M., Huang, Peng, Dang, Uyen T., Hurdle, Julian G., Kondratyuk, Tamara P., Pezzuto, John M., Turkson, James, Cao, Shugeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585240/
https://www.ncbi.nlm.nih.gov/pubmed/28874704
http://dx.doi.org/10.1038/s41598-017-10537-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585240/
https://www.ncbi.nlm.nih.gov/pubmed/28874704
http://dx.doi.org/10.1038/s41598-017-10537-1

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