Immunization of cervidized transgenic mice with multimeric deer prion protein induces self-antibodies that antagonize chronic wasting disease infectivity in vitro

Chronic wasting disease (CWD) is the most contagious prion disease. It is expanding rapidly in North America, was found recently in Europe, and the potential for transmission to humans cannot be excluded yet. We hypothesized that it is possible to prevent peripheral CWD infection and CWD prion shedd...

Descripción completa

Detalles Bibliográficos
Autores principales: Abdelaziz, Dalia H., Thapa, Simrika, Abdulrahman, Basant, Lu, Li, Jain, Shikha, Schatzl, Hermann M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585258/
https://www.ncbi.nlm.nih.gov/pubmed/28874781
http://dx.doi.org/10.1038/s41598-017-11235-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585258/
https://www.ncbi.nlm.nih.gov/pubmed/28874781
http://dx.doi.org/10.1038/s41598-017-11235-8

Ejemplares similares