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Immunization of cervidized transgenic mice with multimeric deer prion protein induces self-antibodies that antagonize chronic wasting disease infectivity in vitro
Chronic wasting disease (CWD) is the most contagious prion disease. It is expanding rapidly in North America, was found recently in Europe, and the potential for transmission to humans cannot be excluded yet. We hypothesized that it is possible to prevent peripheral CWD infection and CWD prion shedd...
Autores principales: | Abdelaziz, Dalia H., Thapa, Simrika, Abdulrahman, Basant, Lu, Li, Jain, Shikha, Schatzl, Hermann M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585258/ https://www.ncbi.nlm.nih.gov/pubmed/28874781 http://dx.doi.org/10.1038/s41598-017-11235-8 |
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