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UPLC-Q-TOF/MS-based metabonomic studies on the intervention effects of aspirin eugenol ester in atherosclerosis hamsters

Based on the pro-drug principle, aspirin and eugenol were used to synthesize aspirin eugenol ester (AEE) by esterification reaction. In present study, the anti-atherosclerosis effects of AEE were investigated in hamsters with the utilization of metabonomic approach based on UPLC-Q-TOF/MS. Biochemica...

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Detalles Bibliográficos
Autores principales: Ma, Ning, Yang, Yajun, Liu, Xiwang, Kong, Xiaojun, Li, Shihong, Qin, Zhe, Jiao, Zenghua, Li, Jianyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585262/
https://www.ncbi.nlm.nih.gov/pubmed/28874840
http://dx.doi.org/10.1038/s41598-017-11422-7