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Innate immune activating ligand SUMOylation affects tumor cell recognition by NK cells

Natural Killer cells are innate lymphocytes involved in tumor immunosurveillance. They express activating receptors able to recognize self-molecules poorly expressed on healthy cells but up-regulated upon stress conditions, including transformation. Regulation of ligand expression in tumor cells mai...

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Detalles Bibliográficos
Autores principales: Zitti, Beatrice, Molfetta, Rosa, Fionda, Cinzia, Quatrini, Linda, Stabile, Helena, Lecce, Mario, de Turris, Valeria, Ricciardi, Maria Rosaria, Petrucci, Maria Teresa, Cippitelli, Marco, Gismondi, Angela, Santoni, Angela, Paolini, Rossella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585267/
https://www.ncbi.nlm.nih.gov/pubmed/28874810
http://dx.doi.org/10.1038/s41598-017-10403-0