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Mapping of Surface-Exposed Epitopes of In Vitro and In Vivo Aggregated Species of Alpha-Synuclein

Aggregated alpha-synuclein is the main component of Lewy bodies, intraneuronal deposits observed in Parkinson’s disease and dementia with Lewy bodies. The objective of the study was to identify surface-exposed epitopes of alpha-synuclein in vitro and in vivo formed aggregates. Polyclonal immunoglobu...

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Detalles Bibliográficos
Autores principales: Almandoz-Gil, Leire, Lindström, Veronica, Sigvardson, Jessica, Kahle, Philipp J., Lannfelt, Lars, Ingelsson, Martin, Bergström, Joakim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585306/
https://www.ncbi.nlm.nih.gov/pubmed/28028735
http://dx.doi.org/10.1007/s10571-016-0454-0