Structural and pharmacological basis for the induction of mitochondrial biogenesis by formoterol but not clenbuterol

Mitochondrial dysfunction is associated with numerous acute and chronic degenerative diseases. The beta-2 adrenergic receptor (β(2)AR) agonist formoterol induces mitochondrial biogenesis (MB), but other β(2)AR agonists, such as clenbuterol, do not. We sought to identify the MB signaling pathway of f...

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Detalles Bibliográficos
Autores principales: Cameron, Robert B., Peterson, Yuri K., Beeson, Craig C., Schnellmann, Rick G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585315/
https://www.ncbi.nlm.nih.gov/pubmed/28874749
http://dx.doi.org/10.1038/s41598-017-11030-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585315/
https://www.ncbi.nlm.nih.gov/pubmed/28874749
http://dx.doi.org/10.1038/s41598-017-11030-5

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