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Cell Spheroids with Enhanced Aggressiveness to Mimic Human Liver Cancer In Vitro and In Vivo

We fabricated a spheroid-forming unit (SFU) for efficient and economic production of cell spheroids. We optimized the protocol for generating large and homogenous liver cancer cell spheroids using Huh7 hepatocellular carcinoma (HCC) cells. The large Huh7 spheroids showed apoptotic and proliferative...

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Detalles Bibliográficos
Autores principales: Jung, Hong-Ryul, Kang, Hyun Mi, Ryu, Jea-Woon, Kim, Dae-Soo, Noh, Kyung Hee, Kim, Eun-Su, Lee, Ho-Joon, Chung, Kyung-Sook, Cho, Hyun-Soo, Kim, Nam-Soon, Im, Dong-Soo, Lim, Jung Hwa, Jung, Cho-Rok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585316/
https://www.ncbi.nlm.nih.gov/pubmed/28874716
http://dx.doi.org/10.1038/s41598-017-10828-7