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Alcohol amplifies ketamine-induced apoptosis in primary cultured cortical neurons and PC12 cells through down-regulating CREB-related signaling pathways

Recreational use of ketamine (KET) has been increasing worldwide. Previous studies have demonstrated that KET induced neurotoxicity; however, few studies have examined how alcohol (ALC) affects KET-induced neurotoxicity. In light of the fact that some KET abusers combine KET with ALC, the present st...

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Detalles Bibliográficos
Autores principales: Zuo, Daiying, Sun, Feng, Cui, Jiahui, Liu, Yumiao, Liu, Zi, Zhou, Xuejiao, Li, Zengqiang, Wu, Yingliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585325/
https://www.ncbi.nlm.nih.gov/pubmed/28874724
http://dx.doi.org/10.1038/s41598-017-10868-z