Knockout of the ATPase inhibitory factor 1 protects the heart from pressure overload-induced cardiac hypertrophy

Mitochondrial ATP synthase catalyzes the coupling of oxidative phosphorylation. Under pathological conditions, ATP synthase hydrolyzes ATP to replenish protons from the matrix into the intermembrane space, sustaining mitochondrial membrane potential. ATPase inhibitory factor 1 (IF1) is a nuclear-enc...

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Detalles Bibliográficos
Autores principales: Yang, Kevin, Long, Qinqiang, Saja, Kamalamma, Huang, Fengyuan, Pogwizd, Steven M., Zhou, Lufang, Yoshida, Masasuke, Yang, Qinglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585346/
https://www.ncbi.nlm.nih.gov/pubmed/28874825
http://dx.doi.org/10.1038/s41598-017-11251-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585346/
https://www.ncbi.nlm.nih.gov/pubmed/28874825
http://dx.doi.org/10.1038/s41598-017-11251-8

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