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Natural (∆(9)-THC) and synthetic (JWH-018) cannabinoids induce seizures by acting through the cannabinoid CB(1) receptor

Natural cannabinoids and their synthetic substitutes are the most widely used recreational drugs. Numerous clinical cases describe acute toxic symptoms and neurological consequences following inhalation of the mixture of synthetic cannabinoids known as “Spice.” Here we report that an intraperitoneal...

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Detalles Bibliográficos
Autores principales: Malyshevskaya, Olga, Aritake, Kosuke, Kaushik, Mahesh K., Uchiyama, Nahoko, Cherasse, Yoan, Kikura-Hanajiri, Ruri, Urade, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585372/
https://www.ncbi.nlm.nih.gov/pubmed/28874764
http://dx.doi.org/10.1038/s41598-017-10447-2