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Modeling protein quaternary structure of homo- and hetero-oligomers beyond binary interactions by homology

Cellular processes often depend on interactions between proteins and the formation of macromolecular complexes. The impairment of such interactions can lead to deregulation of pathways resulting in disease states, and it is hence crucial to gain insights into the nature of macromolecular assemblies....

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Detalles Bibliográficos
Autores principales: Bertoni, Martino, Kiefer, Florian, Biasini, Marco, Bordoli, Lorenza, Schwede, Torsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585393/
https://www.ncbi.nlm.nih.gov/pubmed/28874689
http://dx.doi.org/10.1038/s41598-017-09654-8