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Modeling protein quaternary structure of homo- and hetero-oligomers beyond binary interactions by homology
Cellular processes often depend on interactions between proteins and the formation of macromolecular complexes. The impairment of such interactions can lead to deregulation of pathways resulting in disease states, and it is hence crucial to gain insights into the nature of macromolecular assemblies....
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585393/ https://www.ncbi.nlm.nih.gov/pubmed/28874689 http://dx.doi.org/10.1038/s41598-017-09654-8 |