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RETRACTED ARTICLE: Impact of different promoters, promoter mutation, and an enhancer on recombinant protein expression in CHO cells

In the present study, six commonly used promoters, including cytomegalovirus major immediate-early (CMV), the CMV enhancer fused to the chicken beta-actin promoter (CAG), human elongation factor-1α (HEF-1α), mouse cytomegalovirus (mouse CMV), Chinese hamster elongation factor-1α (CHEF-1α), and phosp...

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Detalles Bibliográficos
Autores principales: Wang, Wen, Jia, Yan-long, Li, Yi-chun, Jing, Chang-qin, Guo, Xiao, Shang, Xue-fang, Zhao, Chun-peng, Wang, Tian-yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585415/
https://www.ncbi.nlm.nih.gov/pubmed/28874794
http://dx.doi.org/10.1038/s41598-017-10966-y