Antifibrotic Effect of Lactulose on a Methotrexate-Induced Liver Injury Model

The most severe side effect of prolonged MTX treatment is hepatotoxicity. The aim of this study is to investigate the effect of lactulose treatment on MTX-induced hepatotoxicity in a rat model. Twenty-four male rats were included in the study. Sixteen rats were given a single dose of 20 mg/kg MTX to...

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Detalles Bibliográficos
Autores principales: Taskin, Banu, Erdoğan, Mümin Alper, Yiğittürk, Gürkan, Günenç, Damla, Erbaş, Oytun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585605/
https://www.ncbi.nlm.nih.gov/pubmed/28912805
http://dx.doi.org/10.1155/2017/7942531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585605/
https://www.ncbi.nlm.nih.gov/pubmed/28912805
http://dx.doi.org/10.1155/2017/7942531

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