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Antifibrotic Effect of Lactulose on a Methotrexate-Induced Liver Injury Model
The most severe side effect of prolonged MTX treatment is hepatotoxicity. The aim of this study is to investigate the effect of lactulose treatment on MTX-induced hepatotoxicity in a rat model. Twenty-four male rats were included in the study. Sixteen rats were given a single dose of 20 mg/kg MTX to...
Autores principales: | Taskin, Banu, Erdoğan, Mümin Alper, Yiğittürk, Gürkan, Günenç, Damla, Erbaş, Oytun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585605/ https://www.ncbi.nlm.nih.gov/pubmed/28912805 http://dx.doi.org/10.1155/2017/7942531 |
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