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Chaperone-Based Therapies for Disease Modification in Parkinson's Disease
Parkinson's disease (PD) is the second most common neurodegenerative disorder and is characterized by the presence of pathological intracellular aggregates primarily composed of misfolded α-synuclein. This pathology implicates the molecular machinery responsible for maintaining protein homeosta...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585656/ https://www.ncbi.nlm.nih.gov/pubmed/28913005 http://dx.doi.org/10.1155/2017/5015307 |