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Chaperone-Based Therapies for Disease Modification in Parkinson's Disease

Parkinson's disease (PD) is the second most common neurodegenerative disorder and is characterized by the presence of pathological intracellular aggregates primarily composed of misfolded α-synuclein. This pathology implicates the molecular machinery responsible for maintaining protein homeosta...

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Detalles Bibliográficos
Autores principales: Friesen, Erik L., De Snoo, Mitch L., Rajendran, Luckshi, Kalia, Lorraine V., Kalia, Suneil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585656/
https://www.ncbi.nlm.nih.gov/pubmed/28913005
http://dx.doi.org/10.1155/2017/5015307