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Intersectin-1s deficiency in pulmonary pathogenesis

Intersectin-1s (ITSN-1s), a multidomain adaptor protein, plays a vital role in endocytosis, cytoskeleton rearrangement and cell signaling. Recent studies have demonstrated that deficiency of ITSN-1s is a crucial early event in pulmonary pathogenesis. In lung cancer, ITSN-1s deficiency impairs Eps8 u...

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Detalles Bibliográficos
Autores principales: Jeganathan, Niranjan, Predescu, Dan, Predescu, Sanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585975/
https://www.ncbi.nlm.nih.gov/pubmed/28874189
http://dx.doi.org/10.1186/s12931-017-0652-4