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The Accelerated Evolution of Lagging Strand Genes Is Independent of Sequence Context

We previously discovered that lagging strand genes evolve faster in Bacillus subtilis (and potentially other bacteria). Lagging strand genes are transcribed in the head-on orientation with respect to DNA replication, leading to collisions between the two machineries that stall replication and can de...

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Detalles Bibliográficos
Autores principales: Merrikh, Christopher N., Weiss, Eli, Merrikh, Houra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585990/
https://www.ncbi.nlm.nih.gov/pubmed/28039230
http://dx.doi.org/10.1093/gbe/evw274