Tetrahydrobiopterin (BH4) deficiency is associated with augmented inflammation and microvascular degeneration in the retina

BACKGROUND: Tetrahydrobiopterin (BH4) is an essential cofactor in multiple metabolic processes and plays an essential role in maintaining the inflammatory and neurovascular homeostasis. In this study, we have investigated the deleterious effects of BH4 deficiency on retinal vasculature during develo...

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Detalles Bibliográficos
Autores principales: Rivera, José Carlos, Noueihed, Baraa, Madaan, Ankush, Lahaie, Isabelle, Pan, Jingyi, Belik, Jaques, Chemtob, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586016/
https://www.ncbi.nlm.nih.gov/pubmed/28874201
http://dx.doi.org/10.1186/s12974-017-0955-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586016/
https://www.ncbi.nlm.nih.gov/pubmed/28874201
http://dx.doi.org/10.1186/s12974-017-0955-x

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