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Redox and Activation of Protein Kinase A Dysregulates Calcium Homeostasis in Pulmonary Vein Cardiomyocytes of Chronic Kidney Disease

BACKGROUND: Chronic kidney disease (CKD) increases the occurrence of atrial fibrillation and pulmonary vein (PV) arrhythmogenesis. Calcium dysregulation and reactive oxygen species (ROS) enhance PV arrhythmogenic activity. The purposes of this study were to investigate whether CKD modulates PV elect...

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Detalles Bibliográficos
Autores principales: Huang, Shih‐Yu, Chen, Yao‐Chang, Kao, Yu‐Hsun, Hsieh, Ming‐Hsiung, Lin, Yung‐Kuo, Chen, Shih‐Ann, Chen, Yi‐Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586294/
https://www.ncbi.nlm.nih.gov/pubmed/28701305
http://dx.doi.org/10.1161/JAHA.117.005701