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Haplodeficiency of Ataxia Telangiectasia Mutated Accelerates Heart Failure After Myocardial Infarction

BACKGROUND: Cell senescence is involved in the process of organ damage and repair; however, the underlying molecular mechanism needs to be further explored. METHODS AND RESULTS: Senescence‐related genes (ie, p21, p53, and ataxia telangiectasia mutated [ATM]) were shown to be elevated after myocardia...

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Detalles Bibliográficos
Autores principales: Jia, Lixin, Zhang, Wenmei, Ma, Youcai, Chen, Boya, Liu, Yan, Piao, Chunmei, Wang, Yuan, Yang, Min, Liu, Tingting, Zhang, Junmeng, Li, Taotao, Nie, Shaoping, Du, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586323/
https://www.ncbi.nlm.nih.gov/pubmed/28724653
http://dx.doi.org/10.1161/JAHA.117.006349