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Chimeric ZHHH neuroglobin acts as a cell membrane‐penetrating inducer of neurite outgrowth

Neuroglobin (Ngb) is a heme protein expressed in the vertebrate brain. We previously engineered a chimeric Ngb protein, in which module M1 of human Ngb is replaced by that of zebrafish Ngb, and showed that the chimeric ZHHH Ngb has a cell membrane‐penetrating activity similar to that of zebrafish Ng...

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Detalles Bibliográficos
Autores principales: Takahashi, Nozomu, Onozuka, Wataru, Watanabe, Seiji, Wakasugi, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586349/
https://www.ncbi.nlm.nih.gov/pubmed/28904863
http://dx.doi.org/10.1002/2211-5463.12271