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The asparagine 533 residue in the outer pore loop region of the mouse PKD2L1 channel is essential for its voltage‐dependent inactivation
Voltage‐dependent inactivation of ion channels contributes to the regulation of the membrane potential of excitable cells. Mouse polycystic kidney disease 2‐like 1 (PKD2L1) forms voltage‐dependent nonselective cation channels, which are activated but subsequently inactivated in response to membrane...
Autores principales: | Shimizu, Takahiro, Higuchi, Taiga, Toba, Toshihiro, Ohno, Chie, Fujii, Takuto, Nilius, Bernd, Sakai, Hideki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586397/ https://www.ncbi.nlm.nih.gov/pubmed/28904867 http://dx.doi.org/10.1002/2211-5463.12273 |
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