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Sirtuin 3 Deficiency Accelerates Hypertensive Cardiac Remodeling by Impairing Angiogenesis

BACKGROUND: Emerging evidence indicates that impaired angiogenesis may contribute to hypertension‐induced cardiac remodeling. The nicotinamide adenine dinucleotide–dependent deacetylase Sirtuin 3 (SIRT3) has the potential to modulate angiogenesis, but this has not been confirmed. As such, the aim of...

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Detalles Bibliográficos
Autores principales: Wei, Tong, Huang, Gaojian, Gao, Jing, Huang, Chenglin, Sun, Mengwei, Wu, Jian, Bu, Juan, Shen, Weili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586452/
https://www.ncbi.nlm.nih.gov/pubmed/28862956
http://dx.doi.org/10.1161/JAHA.117.006114