Matrix Metalloproteinase Inhibitor COL-3 Prevents the Development of Paclitaxel-Induced Hyperalgesia in Mice

OBJECTIVE: To study the potential of chemically modified tetracycline-3 (COL-3), a potent matrix metalloproteinase (MMP) inhibitor, to protect against the development of paclitaxel-induced painful neuropathy and its immunomodulatory effects. MATERIALS AND METHODS: The reaction latency to thermal sti...

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Detalles Bibliográficos
Autores principales: Parvathy, Subramanian S., Masocha, Willias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2012
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586713/
https://www.ncbi.nlm.nih.gov/pubmed/22907189
http://dx.doi.org/10.1159/000341710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586713/
https://www.ncbi.nlm.nih.gov/pubmed/22907189
http://dx.doi.org/10.1159/000341710

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