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Novel Actions of Oxazolidinones: In vitro Screening of a Triazolyloxazolidinone for Anticonvulsant Activity

OBJECTIVE: To test the hypothesis that a triazolyloxazolidinone (PH084) has anticonvulsant activity by examining its effects on in vitro seizure models in the rat hippocampus. MATERIALS AND METHODS: Whole-cell synaptic currents, action potentials and extracellular population spikes (PS) were recorde...

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Detalles Bibliográficos
Autores principales: Kombian, Samuel B., Phillips, Oludotun A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586748/
https://www.ncbi.nlm.nih.gov/pubmed/23257573
http://dx.doi.org/10.1159/000346005