Rectal Carcinoma in a Young Female Patient with Peutz-Jeghers Syndrome: A Case Report

OBJECTIVE: To report a case of rectal cancer in a patient with Peutz-Jeghers syndrome (PJS). CLINICAL PRESENTATION AND INTERVENTION: A 20-year-old woman with intermittent bloody stool of 4 months was admitted for examination. Gastroendoscopy revealed multiple polyps involving the stomach, small inte...

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Detalles Bibliográficos
Autores principales: Tsai, Hsiang-Lin, Lin, Chih-Hung, Cheng, Ya-Lin, Huang, Ching-Wen, Wang, Jaw-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586825/
https://www.ncbi.nlm.nih.gov/pubmed/24008657
http://dx.doi.org/10.1159/000351885
Descripción
Sumario:OBJECTIVE: To report a case of rectal cancer in a patient with Peutz-Jeghers syndrome (PJS). CLINICAL PRESENTATION AND INTERVENTION: A 20-year-old woman with intermittent bloody stool of 4 months was admitted for examination. Gastroendoscopy revealed multiple polyps involving the stomach, small intestine, colon and a rectal adenocarcinoma. A diagnosis of PJS was made based on intestinal polyps with characteristic pathology and melanotic macules on the lips. After surgery and chemotherapy upon follow-up at 8 months, the patient did not have any signs of recurrence. CONCLUSION: This case showed that rectal carcinoma should be considered for young patients with PJS.