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Efficient protein targeting to the inner nuclear membrane requires Atlastin-dependent maintenance of ER topology

Newly synthesized membrane proteins are targeted to the inner nuclear membrane (INM) by diffusion within the membrane system of the endoplasmic reticulum (ER), translocation through nuclear pore complexes (NPCs) and retention on nuclear partners. Using a visual in vitro assay we previously showed th...

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Detalles Bibliográficos
Autores principales: Pawar, Sumit, Ungricht, Rosemarie, Tiefenboeck, Peter, Leroux, Jean-Christophe, Kutay, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587084/
https://www.ncbi.nlm.nih.gov/pubmed/28826471
http://dx.doi.org/10.7554/eLife.28202