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Effect of nerve injury on the number of dorsal root ganglion neurons and autotomy behavior in adult Bax-deficient mice

BACKGROUND: The proapoptotic molecule BAX, plays an important role in mitochondrial apoptotic pathway. Dorsal root ganglion (DRG) neurons depend on neurotrophic factors for survival at early developmental stages. Withdrawal of neurotrophic factors will induce apoptosis in DRG neurons, but this type...

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Detalles Bibliográficos
Autores principales: Lyu, Chuang, Lyu, Gong-Wei, Martinez, Aurora, Shi, Tie-Jun Sten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587150/
https://www.ncbi.nlm.nih.gov/pubmed/28919807
http://dx.doi.org/10.2147/JPR.S133087