Transforming growth factor-β1/Smad3-independent epithelial–mesenchymal transition in type I collagen glomerulopathy

The glomerulofibrotic Col1a2-deficient mouse model demonstrates glomerular homotrimeric type I collagen deposition in mesangial and subendothelial spaces. In this report, we investigate the role of transforming growth factor β1 (TGF-β1) in myofibroblast activation and epithelial–mesenchymal transiti...

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Detalles Bibliográficos
Autores principales: Brodeur, Amanda C, Roberts-Pilgrim, Anna M, Thompson, Kimberlee L, Franklin, Craig L, Phillips, Charlotte L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587152/
https://www.ncbi.nlm.nih.gov/pubmed/28919801
http://dx.doi.org/10.2147/IJNRD.S141393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587152/
https://www.ncbi.nlm.nih.gov/pubmed/28919801
http://dx.doi.org/10.2147/IJNRD.S141393

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