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Transforming growth factor-β1/Smad3-independent epithelial–mesenchymal transition in type I collagen glomerulopathy
The glomerulofibrotic Col1a2-deficient mouse model demonstrates glomerular homotrimeric type I collagen deposition in mesangial and subendothelial spaces. In this report, we investigate the role of transforming growth factor β1 (TGF-β1) in myofibroblast activation and epithelial–mesenchymal transiti...
Autores principales: | Brodeur, Amanda C, Roberts-Pilgrim, Anna M, Thompson, Kimberlee L, Franklin, Craig L, Phillips, Charlotte L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587152/ https://www.ncbi.nlm.nih.gov/pubmed/28919801 http://dx.doi.org/10.2147/IJNRD.S141393 |
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