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Characterization of the microDNA through the response to chemotherapeutics in lymphoblastoid cell lines
Recently, a new class of extrachromosomal circular DNA, called microDNA, was identified. They are on average 100 to 400 bp long and are derived from unique non-repetitive genomic regions with high gene density. MicroDNAs are thought to arise from DNA breaks associated with RNA metabolism or replicat...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587290/ https://www.ncbi.nlm.nih.gov/pubmed/28877255 http://dx.doi.org/10.1371/journal.pone.0184365 |