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Characterization of the microDNA through the response to chemotherapeutics in lymphoblastoid cell lines

Recently, a new class of extrachromosomal circular DNA, called microDNA, was identified. They are on average 100 to 400 bp long and are derived from unique non-repetitive genomic regions with high gene density. MicroDNAs are thought to arise from DNA breaks associated with RNA metabolism or replicat...

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Detalles Bibliográficos
Autores principales:	Mehanna, Pamela, Gagné, Vincent, Lajoie, Mathieu, Spinella, Jean-François, St-Onge, Pascal, Sinnett, Daniel, Brukner, Ivan, Krajinovic, Maja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587290/ https://www.ncbi.nlm.nih.gov/pubmed/28877255 http://dx.doi.org/10.1371/journal.pone.0184365

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