Tankyrase inhibitors suppress hepatocellular carcinoma cell growth via modulating the Hippo cascade

Previous data indicate that Tankyrase inhibitors exert anti-growth functions in many cancer cell lines due to their ability to inactivate the YAP protooncogene. In the present manuscript, we investigated the effect of Tankyrase inhibitors on the growth of hepatocellular carcinoma (HCC) cell lines an...

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Detalles Bibliográficos
Autores principales: Jia, Jiaoyuan, Qiao, Yu, Pilo, Maria G., Cigliano, Antonio, Liu, Xianqiong, Shao, Zixuan, Calvisi, Diego F., Chen, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587291/
https://www.ncbi.nlm.nih.gov/pubmed/28877210
http://dx.doi.org/10.1371/journal.pone.0184068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587291/
https://www.ncbi.nlm.nih.gov/pubmed/28877210
http://dx.doi.org/10.1371/journal.pone.0184068

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