Comparative quantitative proteomic analysis of disease stratified laser captured microdissected human islets identifies proteins and pathways potentially related to type 1 diabetes

Type 1 diabetes (T1D) is a chronic inflammatory disease that is characterized by autoimmune destruction of insulin-producing pancreatic beta cells. The goal of this study was to identify novel protein signatures that distinguish Islets from patients with T1D, patients who are autoantibody positive w...

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Detalles Bibliográficos
Autores principales: Nyalwidhe, Julius O., Grzesik, Wojciech J., Burch, Tanya C., Semeraro, Michele L., Waseem, Tayab, Gerling, Ivan C., Mirmira, Raghavendra G., Morris, Margaret A., Nadler, Jerry L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587329/
https://www.ncbi.nlm.nih.gov/pubmed/28877242
http://dx.doi.org/10.1371/journal.pone.0183908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587329/
https://www.ncbi.nlm.nih.gov/pubmed/28877242
http://dx.doi.org/10.1371/journal.pone.0183908

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