Niclosamide induces protein ubiquitination and inhibits multiple pro-survival signaling pathways in the human glioblastoma U-87 MG cell line

Glioblastoma is the most common and lethal malignant primary brain tumor for which the development of efficacious chemotherapeutic agents remains an urgent need. The anti-helminthic drug niclosamide, which has long been in use to treat tapeworm infections, has recently attracted renewed interest due...

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Detalles Bibliográficos
Autores principales: Cheng, Benxu, Morales, Liza Doreen, Zhang, Yonghong, Mito, Shizue, Tsin, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587337/
https://www.ncbi.nlm.nih.gov/pubmed/28877265
http://dx.doi.org/10.1371/journal.pone.0184324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587337/
https://www.ncbi.nlm.nih.gov/pubmed/28877265
http://dx.doi.org/10.1371/journal.pone.0184324

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