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Niclosamide induces protein ubiquitination and inhibits multiple pro-survival signaling pathways in the human glioblastoma U-87 MG cell line
Glioblastoma is the most common and lethal malignant primary brain tumor for which the development of efficacious chemotherapeutic agents remains an urgent need. The anti-helminthic drug niclosamide, which has long been in use to treat tapeworm infections, has recently attracted renewed interest due...
Autores principales: | Cheng, Benxu, Morales, Liza Doreen, Zhang, Yonghong, Mito, Shizue, Tsin, Andrew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587337/ https://www.ncbi.nlm.nih.gov/pubmed/28877265 http://dx.doi.org/10.1371/journal.pone.0184324 |
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