Culture-induced recurrent epigenetic aberrations in human pluripotent stem cells

Human pluripotent stem cells (hPSCs) are an important player in disease modeling and regenerative medicine. Nonetheless, multiple studies uncovered their inherent genetic instability upon prolonged culturing, where specific chromosomal aberrations provide cells with a growth advantage. These positiv...

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Detalles Bibliográficos
Autores principales: Weissbein, Uri, Plotnik, Omer, Vershkov, Dan, Benvenisty, Nissim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587343/
https://www.ncbi.nlm.nih.gov/pubmed/28837588
http://dx.doi.org/10.1371/journal.pgen.1006979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587343/
https://www.ncbi.nlm.nih.gov/pubmed/28837588
http://dx.doi.org/10.1371/journal.pgen.1006979

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