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Estradiol as a Targeted, Late-Line Therapy in Metastatic Breast Cancer with Estrogen Receptor Amplification

Estradiol is a major regulator of growth for the subset of breast cancers that express the estrogen receptor (ER, ESR1). Strategies to block ER action, via reduction of estradiol or direct inhibition of ER, have shown major success in the prevention and treatment of breast cancer. However, most ER-p...

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Detalles Bibliográficos
Autores principales: Kota, Karthik, Brufsky, Adam, Oesterreich, Steffi, Lee, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587405/
https://www.ncbi.nlm.nih.gov/pubmed/28924522
http://dx.doi.org/10.7759/cureus.1434