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Estradiol as a Targeted, Late-Line Therapy in Metastatic Breast Cancer with Estrogen Receptor Amplification
Estradiol is a major regulator of growth for the subset of breast cancers that express the estrogen receptor (ER, ESR1). Strategies to block ER action, via reduction of estradiol or direct inhibition of ER, have shown major success in the prevention and treatment of breast cancer. However, most ER-p...
Autores principales: | Kota, Karthik, Brufsky, Adam, Oesterreich, Steffi, Lee, Adrian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587405/ https://www.ncbi.nlm.nih.gov/pubmed/28924522 http://dx.doi.org/10.7759/cureus.1434 |
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