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Effects of Food on the Pharmacokinetics of Omega-3-Carboxylic Acids in Healthy Japanese Male Subjects: A Phase I, Randomized, Open-label, Three-period, Crossover Trial

Aims: Omega-3-carboxylic acids (OM3-CA) contain omega-3 free fatty acids, such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), as carboxylic acids. Food intake is known to affect the bioavailability of ethyl ester fatty acid formulations. We conducted a phase I study to investigate th...

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Detalles Bibliográficos
Autores principales: Shimada, Hitoshi, Nilsson, Catarina, Noda, Yoshinori, Kim, Hyosung, Lundström, Torbjörn, Yajima, Toshitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Atherosclerosis Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587524/
https://www.ncbi.nlm.nih.gov/pubmed/28344197
http://dx.doi.org/10.5551/jat.38737