Abnormal Electroretinogram after Kir7.1 Channel Suppression Suggests Role in Retinal Electrophysiology

The KCNJ13 gene encodes the inwardly rectifying potassium channel, Kir7.1. Mutations in this gene cause childhood blindness, in which the a- and b-wave responses of electroretinogram (ERG) are abolished. The ERG a-wave is the light-induced hyperpolarization of retinal photoreceptors, and the b-wave...

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Detalles Bibliográficos
Autores principales: Shahi, Pawan K., Liu, Xinling, Aul, Bryce, Moyer, Andrea, Pattnaik, Akshita, Denton, Jerod, Pillers, De-Ann M., Pattnaik, Bikash R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587531/
https://www.ncbi.nlm.nih.gov/pubmed/28878288
http://dx.doi.org/10.1038/s41598-017-11034-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587531/
https://www.ncbi.nlm.nih.gov/pubmed/28878288
http://dx.doi.org/10.1038/s41598-017-11034-1

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