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Mutation E87Q of the β1-subunit impairs the maturation of the cardiac voltage-dependent sodium channel
Voltage-dependent sodium channels are responsible of the rising phase of the action potential in excitable cells. These membrane integral proteins are composed by a pore-forming α-subunit, and one or more auxiliary β subunits. Mutation E87Q of the β1 subunit is correlated with Brugada syndrome, a ge...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587543/ https://www.ncbi.nlm.nih.gov/pubmed/28878239 http://dx.doi.org/10.1038/s41598-017-10645-y |