Loss of NR2E3 represses AHR by LSD1 reprogramming, is associated with poor prognosis in liver cancer

The aryl hydrocarbon receptor (AHR) plays crucial roles in inflammation, metabolic disorder, and cancer. However, the molecular mechanisms regulating AHR expression remain unknown. Here, we found that an orphan nuclear NR2E3 maintains AHR expression, and forms an active transcriptional complex with...

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Detalles Bibliográficos
Autores principales: Khanal, Tilak, Choi, Kwangmin, Leung, Yuet-Kin, Wang, Jiang, Kim, Dasom, Janakiram, Vinothini, Cho, Sung-Gook, Puga, Alvaro, Ho, Shuk-Mei, Kim, Kyounghyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587550/
https://www.ncbi.nlm.nih.gov/pubmed/28878246
http://dx.doi.org/10.1038/s41598-017-11106-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587550/
https://www.ncbi.nlm.nih.gov/pubmed/28878246
http://dx.doi.org/10.1038/s41598-017-11106-2

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