Immunoregulation by IL-7R-targeting antibody-drug conjugates: overcoming steroid-resistance in cancer and autoimmune disease

Steroid-resistance is a common complication in the treatment of malignancies and autoimmune diseases. IL-7/IL-7R signaling, which regulates lymphocyte growth and survival, has been implicated in the development of malignancies and autoimmune diseases. However, the biological significance of IL-7/IL-...

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Detalles Bibliográficos
Autores principales: Yasunaga, Masahiro, Manabe, Shino, Matsumura, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587554/
https://www.ncbi.nlm.nih.gov/pubmed/28878234
http://dx.doi.org/10.1038/s41598-017-11255-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587554/
https://www.ncbi.nlm.nih.gov/pubmed/28878234
http://dx.doi.org/10.1038/s41598-017-11255-4

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