Time-dependent proteomic and genomic alterations in Toll-like receptor-4-activated human chondrocytes: increased expression of lamin A/C and annexins

Activation of Toll-like receptor-4 (TLR-4) in articular chondrocytes increases the catabolic compartment and leads to matrix degradation during the development of osteoarthritis. In this study, we determined the proteomic and genomic alterations in human chondrocytes during lipopolysaccharide (LPS)-...

Descripción completa

Detalles Bibliográficos
Autores principales: Ha, Seung Hee, Kim, Hyoung Kyu, Anh, Nguyen Thi Tuyet, Kim, Nari, Ko, Kyung Soo, Rhee, Byoung Doo, Han, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587603/
https://www.ncbi.nlm.nih.gov/pubmed/28883757
http://dx.doi.org/10.4196/kjpp.2017.21.5.531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587603/
https://www.ncbi.nlm.nih.gov/pubmed/28883757
http://dx.doi.org/10.4196/kjpp.2017.21.5.531

Ejemplares similares