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Eldecalcitol, an Active Vitamin D(3) Derivative, Prevents Trabecular Bone Loss and Bone Fragility in Type I Diabetic Model Rats

Diabetes mellitus is known to adversely affect the bones and be associated with increased fracture risk. We examined whether eldecalcitol (ELD), an active vitamin D(3) derivative, could inhibit the diabetic bone loss in streptozotocin-induced type I diabetic rats. ELD (10, 20, or 40 ng/kg), alfacalc...

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Detalles Bibliográficos
Autores principales: Takeda, Satoshi, Saito, Mitsuru, Sakai, Sadaoki, Yogo, Kenji, Marumo, Keishi, Endo, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587631/
https://www.ncbi.nlm.nih.gov/pubmed/28624935
http://dx.doi.org/10.1007/s00223-017-0298-8