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Eldecalcitol, an Active Vitamin D(3) Derivative, Prevents Trabecular Bone Loss and Bone Fragility in Type I Diabetic Model Rats
Diabetes mellitus is known to adversely affect the bones and be associated with increased fracture risk. We examined whether eldecalcitol (ELD), an active vitamin D(3) derivative, could inhibit the diabetic bone loss in streptozotocin-induced type I diabetic rats. ELD (10, 20, or 40 ng/kg), alfacalc...
Autores principales: | Takeda, Satoshi, Saito, Mitsuru, Sakai, Sadaoki, Yogo, Kenji, Marumo, Keishi, Endo, Koichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587631/ https://www.ncbi.nlm.nih.gov/pubmed/28624935 http://dx.doi.org/10.1007/s00223-017-0298-8 |
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