Transglutaminase 2 regulates osteoclast differentiation via a Blimp1-dependent pathway

Transglutaminase 2 (TG2) performs multiple reactions, including transamidation, and also plays a role in signal transduction as a GTP-binding protein. In this study, we reveal that TG2 controls osteoclast differentiation and bone homeostasis in mice. Osteoclasts specifically expressed the TG2 isofor...

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Detalles Bibliográficos
Autores principales: Kim, Woo-Shin, Kim, Haemin, Jeong, Eui Man, Kim, Hyung Joon, Lee, Zang Hee, Kim, In-Gyu, Kim, Hong-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587636/
https://www.ncbi.nlm.nih.gov/pubmed/28878266
http://dx.doi.org/10.1038/s41598-017-11246-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587636/
https://www.ncbi.nlm.nih.gov/pubmed/28878266
http://dx.doi.org/10.1038/s41598-017-11246-5

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