A Novel Benzocoumarin-Stilbene Hybrid as a DNA ligase I inhibitor with in vitro and in vivo anti-tumor activity in breast cancer models

Existing cancer therapies are often associated with drug resistance and toxicity, which results in poor prognosis and recurrence of cancer. This necessitates the identification and development of novel therapeutics against existing as well as novel cellular targets. In this study, a novel class of B...

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Detalles Bibliográficos
Autores principales: Hussain, Mohd. Kamil, Singh, Deependra Kumar, Singh, Akhilesh, Asad, Mohd., Ansari, Mohd. Imran, Shameem, Mohammad, Krishna, Shagun, Valicherla, Guru R., Makadia, Vishal, Meena, Sanjeev, Deshmukh, Amit Laxmikant, Gayen, Jiaur R., Imran Siddiqi, Mohammad, Datta, Dipak, Hajela, Kanchan, Banerjee, Dibyendu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587642/
https://www.ncbi.nlm.nih.gov/pubmed/28878282
http://dx.doi.org/10.1038/s41598-017-10864-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587642/
https://www.ncbi.nlm.nih.gov/pubmed/28878282
http://dx.doi.org/10.1038/s41598-017-10864-3

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